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Acid herbicides Acidic Acidic catecholamine metabolites Acifluorfen Adipate esters Alcohol metabolite Aliphatic hydrocarbons Alkaloids Aminoglycoside antibiotics Amphetamines Anabolic steroids Anaesthetic Analgesics Antibiotics Anticoagulant Anticonvulsant Antiepileptics Antimicrobial Antipsychotics Aromatic hydrocarbons B Vitamins BDE-153 BDE-99 Barbiturates Base-neutral herbicides Basic Benzodiazepines Beta blockers Biomarker Brominated Flame Retardants (BFRs) Bronchodilator Cannabinoid Carbamate hypnotic Carbamate muscle relaxant Carbamates Catecholamines Cathinones Chlorinated acids Cocaines Corrosion inhibitors Corticosteroids Designer stimulants Diarrhetic Shellfish Poisoning (DSP) Toxins Dinoseb Diuretics Dried chili Drugs of Abuse EN16691 Analytes EN16693:2015 analytes EPA 1657 analytes EPA 1664 A analytes EPA 1664 B analytes EPA 506 Analytes EPA 548.1 Analytes EPA 549.2 Analytes EPA 608 analytes EPA 625.1 Analytes EPA 8015 Analytes Endocrine disrupter Environmental contaminants Estrogens Explosives Fat Soluble Vitamins Fluoroquinolones Food contaminant Hallucinogen Haloacetic Acids Hexabromobiphenyl Hexane Extractable Material Imidazoline corrosion inhibitor Imidazolines Immunosuppressant Legal highs Lipids Marine Toxins Metanephrines Mycotoxin NBOMes NSAIDs Neutral Nicotine metabolites Nitroimidazoles Opiates Opioid Opioid agonist Organic Compounds Organochlorine pesticides (OCP) Organophosphate Pesticide Over the counter pharmaceuticals PAHs PBDEs PCBs Pain Management Paralytic Shellfish Poisoning (PSP) Toxins Peptides Persistant organic pollutants (POP) Perylene-d12 Pesticides Pharmaceuticals Phenethylamines Phenols Phthalate Metabolites Phthalates Phthalic acid esters Plasticisers Polyaromatic Hydrocarbons (PAH) Polyfluorinated acids Preservative Quaternary Amines RDX SERM (selective estrogen receptor modulator) Semi-Volatile Organics Spice Steroid Hormones Steroid metabolite Stimulants Sympathomimetic amine Synthetic Cannabinoids (SPICE) THC metabolites Thyroid Hormone Tobacco Specific Nitrosamines (TSNAs) Triazine Herbicides Triazines Tricyclic Antidepressant Triphenylmethane Dyes Veterinary drugs Vitamin D Vitamins Water Soluble Vitamins tetryl z-drugs β-agonists β-blockers

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Animal feed Apple juice (clear) Aqueous BSA Barley Biological fluids Bovine kidney Brain Brazil nut Carbonated soft drink (soda) Chicken meat Coffee Dried chili Drinking water Eggs Enzyme powder Fish Food Grain Ground water Groundnut (Peanut) Hair Hemolysed whole blood Honey Hydrolysed urine Infant food (cereal) Infant formula (milk) Liver Maize Meat Meconium Milk Mouse plasma Nuts Olive Oil Oral fluid Pig's Blood Plasma Post-Mortem fluids Post-Mortem tissue Potato chips (crisps) Prawns Saliva Salmon Sediment Serum Shellfish Shrimps Sludge cake Soil Spice Stomach contents Sun Lotion Sunscreen Surface water Synthetic urine Urine Urine (horse) Vegetables Waste water Water Wheat Wheat flour Whole blood Wine (red)

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4 results

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Extraction of Acidic Catecholamine Metabolites in Plasma Using EVOLUTE® EXPRESS ABN Prior to LC-MS/MS Analysis

Part No: AN889 Issued year: 2018 File size: 1.03mb File type: pdf

This application note describes a solid phase extraction protocol for the extraction of three catecholamine metabolites (vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid) from plasma prior to LC-MS/MS detection. The method described in this application achieves high reproducible recoveries and excellent linearity (>0.99) in the range 10-200 ng/mL.

5-hydroxyindoleacetic acid (5-HIAA) 96-well plate Acidic catecholamine metabolites Application Notes Clinical English Homovanillic acid (HVA) LC-MS/MS Plasma Vanillylmandelic acid (VMA)

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Extraction of Acidic Catecholamine Metabolites in Plasma Using ISOLUTE® SLE+ Prior to LC-MS/MS Analysis

Part No: AN888 Issued year: 2017 File size: 0.91mb File type: pdf

This application note describes a supported liquid extraction protocol for the extraction of three acidic catecholamine metabolites (vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid) from plasma prior to LC-MS/MS detection. The method described in this application note achieves high reproducible recoveries (>80%, RSD < 5%) for these analytes in plasma with linearity > 0.995 in the range 2–200 ng/mL.

5-hydroxyindoleacetic acid (5-HIAA) 96-well plate Acidic catecholamine metabolites Application Notes Clinical English Homovanillic acid (HVA) LC-MS/MS Plasma Vanillylmandelic acid (VMA)

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Extraction of Catecholamine Acid Metabolites from Plasma Prior to Analysis Using LC-MS/MS

Part No: P170 Issued year: 2017 File size: 0.58mb File type: pdf

Catecholamine metabolites vanillylmandelic acid (VMA), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) are biomarkers for neuroblastoma and catecholaminesecreting tumors. This poster describes optimization of the method development process to maximize analyte sensitivity in the extraction and quantitation of these metabolites from plasma. Parameters investigated include MRM transitions, chromatography and sample preparation protocols. MSACL EU 2017

5-hydroxyindoleacetic acid (5-HIAA) 96-well plate Acidic catecholamine metabolites Catecholamines Clinical English Homovanillic acid (HVA) LC-MS/MS Plasma Posters Vanillylmandelic acid (VMA)

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Extraction of Catecholamine Acid Metabolites from Plasma Prior to Analysis Using UHPLC-MS/MS

Part No: P176 Issued year: 2018 File size: 0.72mb File type: pdf

Catecholamine metabolites vanillylmandelic acid (VMA), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5 HIAA) are biomarkers for neuroblastoma and catecholamine-secreting tumors. This poster presents optimization of the method development process to maximize analyte sensitivity in the extraction and quantitation of these metabolites from plasma. Sample preparation protocols using solid phase extraction (EVOLUTE EXPRESS ABN and AX) and supported liquid extraction (ISOLUTE SLE+) are presented. MSACL NA 2018 Palm Springs, CA

5-hydroxyindoleacetic acid (5-HIAA) 96-well plate Acidic catecholamine metabolites Catecholamines Clinical English Forensic Homovanillic acid (HVA) LC-MS/MS Plasma Posters Vanillylmandelic acid (VMA)

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