Peptide Chemistry
Peptide Synthesis and Purification
Biotage is the only manufacturer of room temperature peptide synthesizers and microwave peptide synthesizers in both entry level and high throughput configurations. We offer a range of manual, semi-automated and fully automated systems depending on your peptide synthesis needs. Whether you require a system that makes a single peptide or multiple peptides in parallel, we have an instrument to suit your requirements.
Highlighted Products
Biotage® Initiator+ Alstra™
Biotage® Initiator+ Alstra™ is a fully automated microwave peptide synthesizer . With functionality such as Branches, Preactivation and “Edit on the fly”, and options for UV monitoring and MAOS (organic synthesis) capability, this instrument represents best-in-class systems for both small and large scale synthesis of peptides, peptoids, PNA and peptidomimetics.
Biotage® SNAP Bio
Biotage® SNAP Bio flash cartridges were developed with a small particle size (20 μm) and large pore size (300 Å) to provide increased resolution and the effective separation of complex peptide mixtures.
Biotage® Initiator+ SP Wave
“The Initiator+ SP Wave – I think it’s an amazing little beast. Semi-automated, which I think is ideal for an academic lab making lots of bizarre peptides and exotics on a day-to-day basis then it’s a fantastic instrument. You can make PNA and ours has worked amazingly well in terms of the purity of materials obtained” Prof Mark Bradley, School of Chemistry, University of Edinburgh
Syro II
SYRO II is a fully automatic, computer controlled peptide synthesizer utilizing a two arm pipetting robot. Now available with the new Syro Heating Block(s) option!
Syro I
Fully automated computer controlled peptide synthesizer based on a one arm pipetting robot. Syro I is equipped with one type-U reactor block that can accept 2, 5 and 10 ml reactors. An infinitely variable vortexer guarantees an optimal mixing of the reactants. Now available with the new Syro Heating Block(s) option!
HMPB-ChemMatrix®
For peptide acids, we recommend using the HMPB-ChemMatrix as this resin will provide high crude purity and a recovery yield of 90-95%. The Wang-ChemMatrix will produce similar crude peptide purity, but the recovery yield is lower (60-70%). On request, we can provide preloaded HMPB-ChemMatrix resins with all 20 naturally occurring amino acids. Other amino acids can be preloaded on special request.
