Peptide Chemistry
Peptide Synthesis and Purification
Biotage is the only manufacturer of room temperature peptide synthesizers and microwave peptide synthesizers in both entry level and high throughput configurations. We offer a range of manual, semi-automated and fully automated systems depending on your peptide synthesis needs. Whether you require a system that makes a single peptide or multiple peptides in parallel, we have an instrument to suit your requirements.
Highlighted Products
Biotage® Initiator+ Alstra™
Biotage® Initiator+ Alstra™ is a fully automated microwave peptide synthesizer . With functionality such as Branches, Preactivation and “Edit on the fly”, and options for UV monitoring and MAOS (organic synthesis) capability, this instrument represents best-in-class systems for both small and large scale synthesis of peptides, peptoids, PNA and peptidomimetics.
Biotage® Initiator+ SP Wave
“The Initiator+ SP Wave – I think it’s an amazing little beast. Semi-automated, which I think is ideal for an academic lab making lots of bizarre peptides and exotics on a day-to-day basis then it’s a fantastic instrument. You can make PNA and ours has worked amazingly well in terms of the purity of materials obtained” Prof Mark Bradley, School of Chemistry, University of Edinburgh
Syro II
SYRO II is a fully automatic, computer controlled peptide synthesizer utilizing a two arm pipetting robot. Now available with the new Syro Heating Block(s) option!
Biotage® SNAP Bio
This product was withdrawn on October 1st, 2019. Please check out here the corresponding column in the Biotage® Sfär family: C18 media: Biotage® Sfär Bio C18 Duo 300 Å 20 μm or C4 media: Biotage® Sfär Bio C4 Duo 300 Å 20 μm The purification step (RP-HPLC) is one of the main bottlenecks in the peptide synthesis workflow, limited by small loading amounts, long separation times, poor recoveries and high costs. Biotage® Sfär Bio cartridges offer similar performance, in a flash format, at a fraction of the cost. They have an increased loading capability compared to prep RP-HPLC, enabling more peptide to be processed in a single injection and faster, more efficient peptide purification. Biotage® Sfär Bio flash cartridges are a powerful tool to address the purification needs of peptide chemists.
Syro I
Fully automated computer controlled peptide synthesizer based on a one arm pipetting robot. Syro I is equipped with one type-U reactor block that can accept 2, 5 and 10 ml reactors. An infinitely variable vortexer guarantees an optimal mixing of the reactants. Now available with the new Syro Heating Block(s) option!
Alstra™ Remote
Alstra™ Remote is software when installed on a computer provides the user the same intuitive programming interface found on the Biotage® Initiator+ Alstra™ microwave peptide synthesizer.
HMPB-ChemMatrix®
For peptide acids, we recommend using the HMPB-ChemMatrix as this resin will provide high crude purity and a recovery yield of 90-95%. The Wang-ChemMatrix will produce similar crude peptide purity, but the recovery yield is lower (60-70%).
