
Synthesizer | - |
Liquid handling | 10 mL digital syringe pump |
Liquid ports | 8-way valve with 4 outlet ports and 4 reagents/solvents ports |
Valve | 3-way PTFE-valve |
Mixing | Vortex mixer 24 V, 100–600 rpm |
Liquid dispensing | Dispensing plate |
Vessel holder | 24 position U-type reactor block |
Reaction vessels | PP-reactors with PTFE-frits 2 mL, 5 mL, 10 mL |
Vacuum | - |
Vacuum pump | ME 2C |
Vacuum waste container | 10 L Nalgene bottle |
Controller | - |
Type | Microprocessor |
Display | LC-display with 40 x 16 characters |
Presets | 10 program files with 20 steps. Automatic fill and wash procedur |
Manual mode | Yes |
Power Requirements | - |
Input voltages | 10–220 VAC +/- 10 % |
Power supply | 24 V max. 150 W |
Dimensions (WxDxH) | - |
Synthesizer | 540 mm x 250 mm x 345 mm |
Controller | 195 mm x 65 mm x 170 mm |
The MultiSynTech Company develops accessories for peptide and combinatorial chemistry, as well as for automated synthesis. Our synthesis machines are used for parallel synthesis on solid phase as well as for solution chemistry. The multiple, fully automatic synthesis robot SYRO and the semi-automatic synthesis stations SAP, SAM and SAS are used in wide areas of organic chemistry, medicinal chemistry and also academic research for the synthesis of peptides and substance libraries for small molecules.
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Die Firma MultiSynTech entwickelt Hilfsmittel für die Peptid- und kombinatorische Chemie sowie für automatisierte Synthesen. Unsere Syntheseautomaten werden für die Parallelsynthese an fester Phase, wie auch für die Chemie in Lösung verwendet. Der multiple, vollautomatische Syntheseroboter Syro, die halbautomatischen Synthesestationen SAP, SAM und SAS werden in weiten Bereichen der organischen Chemie, der medizinischen Chemie wie auch in der Hochschulforschung für die Synthese von Peptiden und Substanzbibliotheken kleiner Moleküle eingesetzt. Für Anwendungen, die eine große Anzahl von Peptiden mit nur geringen Substanzmengen erfordern, haben wir die Tip-Synthese- und Spot-Synthese-Module entwickelt, die im Handumdrehen auf dem Syro installiert werden können. In Zusammenarbeit mit führenden Herstellern von Chemikalien haben wir eine Palette von Peptidreagenzien aufgebaut, die sowohl qualitativ als auch preislich für unsere Kunden Vorteile bietet.
Tags: Brochures,
German
Biotage® Initiator+ Alstra™ is a fully automated microwave peptide synthesizer . With functionality such as Branches, Preactivation and “Edit on the fly”, and options for UV monitoring and MAOS (organic synthesis) capability, this instrument represents best-in-class systems for both small and large scale synthesis of peptides, peptoids, PNA and peptidomimetics.
PAL-ChemMatrix is highly recommended for microwave synthesis. Under microwave heating conditions, such as the Biotage Initiator, the PAL-ChemMatrix provides higher purity peptides than the Rink Amide ChemMatrix. For manual synthesis or non-microwave synthesis, we recommend using the Rink Amide ChemMatrix resin.
“The Initiator+ SP Wave – I think it’s an amazing little beast. Semi-automated, which I think is ideal for an academic lab making lots of bizarre peptides and exotics on a day-to-day basis then it’s a fantastic instrument. You can make PNA and ours has worked amazingly well in terms of the purity of materials obtained”
Prof Mark Bradley, School of Chemistry, University of Edinburgh
Fully automated computer controlled peptide synthesizer based on a one arm pipetting robot. Syro I is equipped with one type-U reactor block that can accept 2, 5 and 10 ml reactors. An infinitely variable vortexer guarantees an optimal mixing of the reactants.
Now available with the new Syro Heating Block(s) option!
SYRO II is a fully automatic, computer controlled peptide synthesizer utilizing a two arm pipetting robot.
Now available with the new Syro Heating Block(s) option!
SAM is a semi-automated multiple (parallel) peptide synthesis system that can produce 24 peptides in parallel.
The 24-position U-block reactor can be operated with 2 mL, 5 mL, or 10 mL disposable polypropylene reactors (with PTFE frits) for FMOC-synthesis between 5-300 micromole scale. Four different solvents and reagents can be pumped into the reaction flask. A digital syringe pump provides accurate dispensing of reagents. A special dispensing plate allows the reagents and solvents to be distributed into the reactor vials. The liquid distribution proceeds in parallel for 6 reactors at a time. The infinitely variable vortexer guarantees a homogeneous mixing of the reactants. The SAM is controlled through an external controller. The controller is equipped with an LCD display with 40 x 16 characters and six function keys, and is easy to use and stores 10-programs each with up 20-steps.
All important system control functions can be used directly in manual mode without a long familiarization period with the complicated control software. Complex single step sequences are linked to a single key command. Complete syntheses-cycles can be processed automatically by linking up to 20 key commands to a program sequence. Ten of these individual programs can be saved on the SAM and remain available to the user.
The controller for SAM is equipped with a 40 x 16 character LCD display and six function keys. The function keys can be used for particular commands as well as the creation and execution of complex programs. For the manual addition of amino acids, we have written a simple PC program that creates and prints a pipetting raster which helps make pipetting safer.
SAM is a semi-automated multiple (parallel) peptide synthesizer producing up to 24 peptides in parallel. The 24-position U-block reactor can be operated with 2 mL, 5 mL, or 10 mL disposable polypropylene reactors (with PTFE frits) for Fmoc-synthesis between 5 and 300 μmol per reactor vial. The U-type reactor block and reactor vials are the same used on the fully automated systems Syro I and II. Four individual solvents and reagents can be pumped into the reaction flask. A digital syringe pump provides accurate dispensing of reagents while a special dispensing plate allows the reagents and solvents to be distributed into the reactor vials. The liquid distribution proceeds in parallel for 6 reactors at a time, with the variable vortexer guaranteeing homogeneous mixing of the reactants.