The compound 4 Methylimidazole (4-MeI) is made during the production of caramel color commonly found in foods and beverages, especially sodas. The Codex Alimentarius of the World Health Organization sets a limit of 250 mg/kg of 4-MeI. Also, the state of California has added 4-MeI to its Prop 65 list at an exposure level of 29 μg/day. This study looks at 4-MeI levels in sodas and malt sodas which are sold in and outside the state of California. The first section, included in this poster, describes the performance of automated solid phase extraction of 4-MeI using conventional HPLC/MS detection. ASMS 2018, San Diego, CA

4-Methylimidazole (4-MEI) Carbonated soft drink (soda) Column English Food Food contaminant LC-MS/MS Posters

This poster demonstrates a novel, sensitive, cost effective and rugged method for the analysis of acrylamide in coffee and potato chips (crisps) using supported liquid extraction prior to LC-MS/MS analysis. It demonstrates extraction from coffee down to a concentration of 1 ng/mL and in potato chips to a level of 10 ng/g (ppb). ASMS 2014

Acrylamide Coffee Column English Food Food contaminant LC-MS/MS Posters Potato chips (crisps)

This application note describes a Supported Liquid Extraction (SLE) protocol for the extraction of acrylamide from coffee using ISOLUTE® SLE+ columns with LC-MS/MS detection. The method described in this application note achieves high recoveries of acrylamide in coffee. The method is sensitive enough to measure levels as low as 1 ng/mL in coffee (solution), 25 ppb in ground coffee (solid) or 125 ppb in instant coffee (solid, traditional or decaffeinated) and gives good selectivity from what is a challenging matrix.

Acrylamide Application Notes Coffee Column English Food Food contaminant LC-MS/MS

This method describes the clean-up of acrylamide from cooked foodstuffs, using a multimode retention mechanism (hydrophobic, cation and anion exchange) for retention of interfering food components. The analytical technique is LC-MS-MS. ISOLUTE, MULTIMODE, SPE, FOOD, FOOD SCARE

Acrylamide Application Notes Column Food Food Food contaminant LC-MS/MS

This application note describes a novel approach to the extraction of acrylamide from potato chips (crisps) using ISOLUTE SLE+ supported liquid extraction columns, with analysis by LC-MS/MS.

Acrylamide Application Notes Column English Food Food contaminant LC-MS/MS Potato chips (crisps)

This application note describes the extraction of melamine from biological fluids using EVOLUTE CX. Sustained melamine exposure can result in kidney stones and renal failure, with the young being most susceptible. food scare, Melamine, China, kidney failure, renal failure, protein, Biotage, EVOLUTE,

Application Notes Biological fluids Column Food Food contaminant LC-MS/MS Melamine

This application note describes the extraction of melamine from biological fluids using EVOLUTE CX. Melamine's low cost and high nitrogen content has led to exploitation in various sections of the food industry, most notably involving dairy products. Biotage, cation exchange, oasis, food scare, china,

Application Notes Column Food Food contaminant LC-MS/MS Melamine Milk

Melamine is traditionally used in making plastics, however, it’s low cost and high nitrogen content has led to exploitation in various sections of the food industry, most notably involving dairy products. Sustained melamine exposure can result in kidney stones and renal failure, with the young being most susceptible. This application note has been optimized on the RapidTrace+; an updated version of the current RapidTrace software which allows the system to process smaller bed heights than were previously possible. The application note shows recoveries of 88-90% with RSDs <10%. Melamine, food scare, china, EVOLUTE, cation exchange, RapidTrace, Automation, SPE, sample prep,

Application Notes Column Food Food contaminant LC-MS/MS Melamine Milk RapidTrace

The United States Food & Drug Administration (FDA) regulates the approval of color additives for their safe use in foods, cosmetics, pharmaceuticals/drugs, and medical devices. The Federal Food, Drug, and Cosmetic Act (FD&C Act) contains provisions for what color additives are required to be certified. These provisions are monitored by the FDA, and through the Code of Federal Regulations (CFR), the FDA releases information on new color additives and new uses for certified color additives.

Application Notes English Food Food Food Additives Food Colours Food contaminant SmartPrep