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Biotage® Sfär Silica D

The column for high quality and flexibility in standard separations

Loading Biotage® Sfär28
FSRD-0445-0050 FSRD-0445-0025 FSRD-0445-0010 FSRD-0445-0005

Biotage® Sfär Silica D is the ideal solution for standard separations that require a reliable normal phase media, with the high quality standard of Biotage and the flexibility of the accessible columns.


Biotage® Sfär Silica D - Duo 60 μm is the ideal solution for standard separations that require a reliable normal phase media and the flexibility of loading the samples in different ways.

Biotage® is a pioneer in Flash Purification, in 1994 we were the first manufacturer of pre-packed column for flash purification. Our history and knowledge goes back much further, starting in 1969, and ranging from analytical to organic chemistry, with reliability and high quality as standard over the years.

Sfär means “Sphere” in the Swedish mother tongue of Biotage, and it has been chosen as the name for our latest columns as they contain spherical silica. Spherical silica has many advantages, the most important being its higher surface area compared to irregular silica, which translates into higher loading capacities, tighter elution bands and purer fractions.

Learn more here about how particle shape and size impact flash column chromatography.

The Silica contained in the Sfär columns is of the highest quality, as you would expect from the pioneer of flash purification and the first manufacturer of pre-packed columns. Sfär columns are quality tested to ensure they meet stringent performance criteria, including efficiency and peak symmetry. Each CE-marked column is created using inert, food grade plastics for lower extractables, cleaner fractions, and packed to provide excellent resolution alongside tolerance of  higher operating pressures (as high as 17 bar).

D stands for Duo (=Two), as Biotage Sfär gives you the dual possibility of liquid loading and drying loading, even though you have more than two possibilities of filling your column, there are actually six: learn more here