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Biotage ZIP® Sphere

High Performance, Low Pressure Flash Cartridge

Biotage ZIP® Sphere cartridges contain Biotage® KP-Sphere™, a proprietary spherical silica which is manufactured under a new process that delivers 40% more surface area (700 m2/g), no fines, and remarkably low back pressure. Typical flash cartridges use silica with a surface area of 500 m2/g and irregular particle sizes. The smallest particles or fines cause higher back pressure, lower flow rates and lower capacity.


  • High sample load compared to irregular silica particles
  • Time to purify is reduced
  • Less solvent required
  • Reduced purification costs 

Available in sizes from 5 g to 120 g